Anti-Human ALCAM (Clone 105901)
Anti-Human ALCAM (Clone 105901) (A381-GRP)
Products
Description
This protein is a member of the immunoglobulin gene superfamily expressed by leukocytes after cell activation and thymic epithelial cells. In the nomenclature of CD antigens this protein has been given the designation CD166. ALCAM is a ligand for the lymphocyte antigen CD6 but also engages in homophilic interactions. Mouse ALCAM shows an overall identity of 93 % with the human protein. ALCAM has been identified independently as MEMD. mRNA transcripts encoding murine ALCAM are expressed in the brain, lung, liver, and the kidney, as well as by activated leukocytes and a number of cell lines. A rat monoclonal antibody specific for murine ALCAM binds to both activated CD4(+) and CD8(+) T-cells. The antigen is expressed on natural killer cells, thymocytes, platelets, B-cells and T-cells after cell activation, eosinophils, fibroblasts, endothelial cells, keratinocytes, monocytes after cell activation, neurons. The ligand for CD166 is CD6.
Specifications
| Manufacturer Cat# | A381 |
|---|---|
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Activated Leukocyte Cell Adhesion Molecule CD166 MEMD SC-1/DM-GRASP/BEN KG-CAM 105901 ALCAM Human Anti-Human ALCAM |
| Isotype | IgG1 |
| Clone | 105901 |
| Antibody Type | Monoclonal |
| Applications | ELISA Indirect, FA, WB |
| Antigen | Expressed on activated T & b cells, activated monocytes, epithelial cells, fibroblasts, and neurons. |
| Storage | -20°C to -70°C |
| Protein | ALCAM |