Anti-GSK3-α (Phospho-Ser21) Antibody (43007)
£398.44
Anti-GSK3-α (Phospho-Ser21) Antibody (43007) (43007-100ul)
Product
| Cat # 43007-100ul | Size 100μl |
Price
£398.44
|
Qty
|
Description
GSK3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK3 alpha and GSK3 beta, which are structurally similar, but functionally non-identical. GSK3alpha is inhibited by phosphorylation at S21 by Akt and other kinases. Dysregulated GSK3 has been implicated in several diseases including type II diabetes, Alzheimers disease, and cancer.
Specifications
| Manufacturer Cat# | 43007 |
|---|---|
| Product Size | 100μl |
| Concentration | 1.0 mg/ml |
| Formulation | PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Target | GSK3-α (Phospho-Ser21) |
| Applications | IHC, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. |