Anti-GRP170 [Clone 6E3-2C3]
£324.38
Anti-GRP170 [Clone 6E3-2C3] (11148-100ug)
Product
| Cat # 11148-100ug | Size 100 µg |
Price
£324.38
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Qty
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Description
Grp170 is a major chaperone/stress protein resident in the ER. It is distantly related in sequence to both hsp110 and hsp70 families, but represents the Grp170 stress protein family. Studies have suggested that Grp170 is an important element of the protein processing machinery of the ER. Unlike Hsp110 and Hsp70, Grp170 has two distinct chaperoning domains; a classic beta-sheet peptide binding domain, with some COOH- terminal sequence, and a COOH-terminal alpha-helical domain. Like other members of the Hsp70 superfamily, Grp170 can elicit anti-tumor immune responses most likely by chaperoning antigenic peptide and binding to receptor(s) on antigen-presenting cells (APC).
Specifications
| Manufacturer Cat# | 11148 |
|---|---|
| Product Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Formulation | PBS, pH 7.4, 0.1% sodium azide, 50% glycerol. Purified by Protein G affinity chromatography. |
| Clone | 6E3-2C3 |
| Target | Grp170 |
| Applications | ELISA, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze-thaw cycles. |