Anti-Gonadotropin Releasing Hormone Antibody (19302)
Anti-Gonadotropin Releasing Hormone Antibody (19302) (19302-GRP)
Products
Description
Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone (LHRH), is a 10 amino acid neurohormone produced in the hypothalamus. GnRH stimulates the synthesis and secretion of the two gonadotropins—luteinizing hormone (LH) and follicle stimulating hormone (FSH)—by the anterior pituitary gland. Characteristic of all releasing hormones, and most striking in the case of GnRH, is the phenomenon of pulsatile secretion. Under normal circumstances, GnRH is released in pulses at intervals of about 90 to 120 minutes. Abnormalities in the pulsatile secretion of GnRH result in subnormal fertility and abnormal or absent menstruation. Constant administration of GnRH suppresses gonadotropin secretion, which has therapeutic benefits in certain patients, such as children with precocious puberty and men with prostate cancer.
Specifications
| Manufacturer Cat# | 19302 |
|---|---|
| Concentration | Lot Specific |
| Formulation | This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added. |
| Clone | LHRH13-372.14 |
| Target | Gonadotropin Releasing Hormone |
| Applications | ELISA, IHC, RIA |
| Storage | This antibody is stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. |
| Protein | Gonadotropin Releasing Hormone |