Anti-Glycogen Phosphorylase, brain, Antibody (13806) (13806-50ug)

Glycogen phosphorylase (GP) removes and converts one glucose molecule from glycogen to glucose-1-phosphate. Mammalian GPs are found in at least three isozymic forms that are distinguished by functional and structural properties as well as by the tissues in which they are preferentially expressed. The brain isozyme of GP is associated primarily with providing an emergency glucose supply during periods of anoxia or hypoglycemia. A549 non-small cell lung carcinoma cells express solely the brain isozyme of GP and have been used to investigate inhibitors of GP that retard cell growth.