ABRAXAS1 antibody
£227.50
ABRAXAS1 antibody (FNab02974)
Product
| Cat # FNab02974 | Size 100ug |
Price
£227.50
|
Qty
|
Description
Involved in DNA damage response and double-strand break(DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab02974 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | family with sequence similarity 175, member A |
| Alternate Names | BRCA1-A complex subunit Abraxas 1|Coiled-coil domain-containing protein 98|Protein FAM175A|ABRAXAS1|ABRA1|CCDC98|FAM175A |
| Calculated MW | 46 kDa |
| Protein ID | Q6UWZ7 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Recommended dilution | WB: 1:500-1:2400; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Gene ID | 84142 |