PDIA3 antibody
£210.00
PDIA3 antibody (FNab02858)
Product
| Cat # FNab02858 | Size 100ug |
Price
£210.00
|
Qty
|
Description
PDIA3, also named as P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58 and PI-PLC, is a member of the PDI family, participates in the oxidation, reduction, and isomerization of disulfide bonds for correct folding of secretory proteins before modification and transport in the endoplasmic reticulum. It is associated with apoptosis or inhibition of cancer cell growth. PDIA3 was once thought to be a phospholipase; however, it has been demonstrated that this protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and PDIA3 mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Specifications
| Manufacturer Cat# | FNab02858 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | protein disulfide isomerase family A, member 3 |
| Alternate Names | Protein disulfide-isomerase A3|58 kDa glucose-regulated protein|58 kDa microsomal protein (p58)|Disulfide isomerase ER-60|Endoplasmic reticulum resident protein 57 (ER protein 57, ERp57)|Endoplasmic reticulum resident protein 60 (ER protein 60, ERp60)|PDIA3|ERP57|ERP60|GRP58 |
| Calculated MW | 57 kDa |
| Protein ID | P30101 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, FC, IF, IHC, IP, WB |
| Recommended dilution | WB: 1:500-1:2400; IP: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:20-1:200 |