Anti-DUX4 Antibody (57100)
£365.63
Anti-DUX4 Antibody (57100) (57100-100ug)
Product
| Cat # 57100-100ug | Size 100 µg |
Price
£365.63
|
Qty
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Description
Facioscapulohumeral muscular dystrophy (FSHD) is caused by the deletion of a subset of D4Z4 macro-satellite repeats on chromosome 4. Each repeat contains a retrogene encoding the double-homeobox factor DUX4. DUX4 expression is epi- genetically suppressed in differentiated tissues, and the residual DUX4 transcripts are spliced to remove the carboxyterminal domain that has been associated with cell toxicity. In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues.
Specifications
| Manufacturer Cat# | 57100 |
|---|---|
| Product Size | 100 µg |
| Concentration | Lot Specific |
| Formulation | This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added. |
| Clone | P4H2 |
| Target | DUX4 |
| Applications | IF, IHC, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Protein | DUX4 |