Anti-Copper-Transporting ATPase2 Antibody (56517)
£464.06
Anti-Copper-Transporting ATPase2 Antibody (56517) (56517-100ug)
Product
| Cat # 56517-100ug | Size 100 µg |
Price
£464.06
|
Qty
|
Description
The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from cells. ATP7b (also known as Copper-Transporting ATPase2) transports copper in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene: A is found in the liver, kidney and brain, the shorter form B is found in brain, and the third isoform, known as WND/140KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver.
Specifications
| Manufacturer Cat# | 56517 |
|---|---|
| Product Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Formulation | PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.Purified by Protein G affinity chromatography. |
| Clone | S62-29 |
| Target | Copper-Transporting ATPase2 |
| Applications | ICC, IF, IHC, IP, WB |
| Storage | This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles. |