CNTN1 antibody
£210.00
CNTN1 antibody (FNab01821)
Product
| Cat # FNab01821 | Size 100ug |
Price
£210.00
|
Qty
|
Description
Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain(NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth(By similarity).
Specifications
| Manufacturer Cat# | FNab01821 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | contactin 1 |
| Alternate Names | Contactin-1|Glycoprotein gp135|Neural cell surface protein F3|CNTN1 |
| Calculated MW | 135 kDa |
| Protein ID | Q12860 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Recommended dilution | WB: 1:500-1:2000 |
| Gene ID | 1272 |