CHTF18 antibody
£227.50
CHTF18 antibody (FNab01701)
Product
| Cat # FNab01701 | Size 100ug |
Price
£227.50
|
Qty
|
Description
Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C(CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A(RPA) and by proliferating cell nuclear antigen(PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.
Specifications
| Manufacturer Cat# | FNab01701 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | CTF18, chromosome transmission fidelity factor 18 homolog |
| Alternate Names | Chromosome transmission fidelity protein 18 homolog (hCTF18)|CHL12|CHTF18|C16orf41|CTF18 |
| Calculated MW | 120 kDa |
| Protein ID | Q8WVB6 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Recommended dilution | WB: 1:500-1:1000; IHC: 1:20-1:200 |
| Gene ID | 63922 |