Anti-Canine PD-1 [Clone JC053]
£431.25
Anti-Canine PD-1 [Clone JC053] (34090-100ug)
Product
| Cat # 34090-100ug | Size 100 µg |
Price
£431.25
|
Qty
|
Description
Each year, thousands of dogs are diagnosed with cancer. Canine cancers bear many of the
hallmarks of human cancers including tissue location, tumor progression, and response to
chemotherapy and radiation. Unfortunately, canine lymphocyte populations are not as well
defined as human lymphocytes, and reagents that target immune checkpoint pathways are not
yet widely available for veterinary research. Interruption of the programmed death 1 (PD-1) /
programmed death ligand 1 (PD-L1) pathway is an established and effective therapeutic strategy
in human oncology and may be effective for treating canine cancers as well.
Specifications
| Manufacturer Cat# | 34090 |
|---|---|
| Product Size | 100 µg |
| Concentration | Lot Specific |
| Formulation | PBS, pH 7.4. |
| Clone | JC053 |
| Target | PD-1 |
| Applications | FACS, IHC, Inhibition |
| Antigen | PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. |
| Storage | This antibody is stable for at least one (1) year at -20°C to-70°C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles. |