Anti-Beclin 2 Antibody (23011)
£456.56
Anti-Beclin 2 Antibody (23011) (23011-100ug)
Product
| Cat # 23011-100ug | Size 100 µg |
Price
£456.56
|
Qty
|
Description
Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Beclin 2 is an Atg6/Beclin family member that functions in two distinct lysosomal degradation pathways, autophagy and the downregulation of certain seven- transmembrane-spanning GPCRs. Its role in GPCR lysosomal degradation does not involve Beclin 1 or other Beclin 1/2-interacting proteins such as ATG14 and VPS34 that function in autophagy. Its role in lysosomal degradation also appears to differ from other autophagy- independent functions previously described for yeast Atg6/Vps30 or mammalian Beclin 1, such as vacuolar protein sorting and EGFR degradation.
Specifications
| Manufacturer Cat# | 23011 |
|---|---|
| Product Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Formulation | PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. |
| Applications | ICC/IF, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles. |
| Protein | Beclin 2 |