Anti-Bcl-xL (Phospho-Ser62) Antibody (43066)
£398.44
Anti-Bcl-xL (Phospho-Ser62) Antibody (43066) (43066-100ul)
Product
| Cat # 43066-100ul | Size 100μl |
Price
£398.44
|
Qty
|
Description
B-cell lymphoma-extra large (Bcl-xl, or BCL2-like 1 isoform 1) is a transmembrane protein in the mitochondria. It is a member of the Bcl-2 family of proteins and acts as a pro-survival protein by preventing the release of mitochondrial cytochrome c, which would lead to caspase activation. Relative amounts of pro- and anti-survival Bcl-2 family proteins define whether a cell will undergo cell death: if more Bcl-xL is present, then pores are non-permeable to pro-apoptotic molecules and the cell survives.
Specifications
| Manufacturer Cat# | 43066 |
|---|---|
| Product Size | 100μl |
| Concentration | 1.0 mg/ml |
| Formulation | PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Target | Bcl-xL (Phospho-Ser62) |
| Applications | IF, IHC, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. |