Anti-Bcl-3 Antibody (11067)
£353.44
Anti-Bcl-3 Antibody (11067) (11067-100ug)
Product
| Cat # 11067-100ug | Size 100 µg |
Price
£353.44
|
Qty
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Description
The gene encoding Bcl-3 was first identified as the gene altered in some cases of chronic B cell lymphocytic leukemia and was later found to belong to the IkappaB subfamily of inhibitors of NFkappaB transcription factors. Bcl- 3 does not have DNA-binding activity, but it interacts with NFkappaB1 and NFkappaB2 which, when bound to DNA, repress gene transcription. Therefore, Bcl-3 may promote gene expression that is repressed by members of the NFkappaB family. Bcl-3 RNA is highly expressed in spleen and liver with lower levels of expression in heart, skeletal muscle, lung, kidney, and testes.
Specifications
| Manufacturer Cat# | 11067 |
|---|---|
| Product Size | 100 µg |
| Concentration | Lot Specific |
| Formulation | This monoclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.2 - 7.4 with no carrier protein or preservatives added. |
| Clone | 150-3.5 |
| Target | Bcl-3 |
| Applications | ELISA, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. |
| Protein | Bcl-3 |