Anti-BAD (Phospho-Ser136) Antibody (43068)
£398.44
Anti-BAD (Phospho-Ser136) Antibody (43068) (43068-100ul)
Product
| Cat # 43068-100ul | Size 100μl |
Price
£398.44
|
Qty
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Description
The protein encoded by the BAD gene is a member of the Bcl-2 family whose members are regulators of programmed cell death. BAD protein positively regulates cell apoptosis by forming heterodimers with Bcl-xL and Bcl-2 and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin, were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Specifications
| Manufacturer Cat# | 43068 |
|---|---|
| Product Size | 100μl |
| Concentration | 1.0 mg/ml |
| Formulation | PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Target | BAD (Phospho-Ser136) |
| Applications | IHC, WB |
| Storage | This antibody is stable for at least one (1) year at -20°C. |