ARHGAP10 antibody
£245.00
ARHGAP10 antibody (FNab00546)
Product
| Cat # FNab00546 | Size 100ug |
Price
£245.00
|
Qty
|
Description
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death(By similarity).
Specifications
| Manufacturer Cat# | FNab00546 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Rho GTPase activating protein 10 |
| Alternate Names | Rho GTPase-activating protein 10|GTPase regulator associated with focal adhesion kinase 2 (GRAF2)|Graf-related protein 2|Rho-type GTPase-activating protein 10|ARHGAP10|GRAF2 |
| Calculated MW | 89 kDa |
| Protein ID | A1A4S6 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Recommended dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Gene ID | 79658 |