SNCA antibody
£227.50
SNCA antibody (FNab00345)
Product
| Cat # FNab00345 | Size 100ug |
Price
£227.50
|
Qty
|
Description
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Specifications
| Manufacturer Cat# | FNab00345 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | synuclein, alpha (non A4 component of amyloid precursor) |
| Alternate Names | Alpha-synuclein|Non-A beta component of AD amyloid|Non-A4 component of amyloid precursor (NACP)|SNCA|NACP|PARK1 |
| Calculated MW | 15 kDa |
| Protein ID | P37840 |
| Reactivity | Human, Rat |
| Applications | ELISA, IF, IHC, WB |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Gene ID | 6622 |