ALKBH7 antibody
£210.00
ALKBH7 antibody (FNab00315)
Product
| Cat # FNab00315 | Size 100ug |
Price
£210.00
|
Qty
|
Description
May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110(in vitro), but this activity may be due to the absence of the true substrate(PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death(PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage(PubMed:23666923). Does not display DNA demethylase activity(PubMed:23666923). Involved in fatty acid metabolism(By similarity).
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00315 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | alkB, alkylation repair homolog 7(E. coli) |
| Alternate Names | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial|Alkylated DNA repair protein alkB homolog 7|Spermatogenesis cell proliferation-related protein|Spermatogenesis-associated protein 11|ALKBH7|ABH7|SPATA11 |
| Calculated MW | 25 kDa |
| Protein ID | Q9BT30 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Recommended dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
| Gene ID | 84266 |