ALKBH5 antibody
£210.00
ALKBH5 antibody (FNab00314)
Product
| Cat # FNab00314 | Size 100ug |
Price
£210.00
|
Qty
|
Description
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity).
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00314 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | alkB, alkylation repair homolog 5(E. coli) |
| Alternate Names | RNA demethylase ALKBH5|Alkylated DNA repair protein alkB homolog 5|Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5|ALKBH5|ABH5|OFOXD1 |
| Calculated MW | 51 kDa |
| Protein ID | Q6P6C2 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Recommended dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
| Gene ID | 54890 |