AKR1C4 antibody
£227.50
AKR1C4 antibody (FNab00263)
Product
| Cat # FNab00263 | Size 100ug |
Price
£227.50
|
Qty
|
Description
Catalyzes the transformation of the potent androgen dihydrotestosterone(DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol(3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone(kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00263 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | aldo-keto reductase family 1, member C4(chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) |
| Alternate Names | Aldo-keto reductase family 1 member C4|3-alpha-hydroxysteroid dehydrogenase type I (3-alpha-HSD1)|3alpha-hydroxysteroid 3-dehydrogenase|Chlordecone reductase (CDR)|Dihydrodiol dehydrogenase 4 (DD-4, DD4)|HAKRA|AKR1C4|CHDR |
| Calculated MW | 37 kDa |
| Protein ID | P17516 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, WB |
| Recommended dilution | WB: 1:1000-1:10000; IF: 1:10-1:100 |
| Gene ID | 1109 |