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AKR1C2 antibody

£245.00

AKR1C2 antibody (FNab10474)

Product

Cat #  FNab10474 Size  100ug Price 
£245.00
Qty 

Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

Manufacturer FineTest
Manufacturer Cat# FNab10474
Product Size 100ug
Antibody Type Polyclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Immunogen affinity purified
Purity ≥95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Immunogen Aldo-keto reductase family 1 member C2
Alternate Names Aldo-keto reductase family 1 member C2|3-alpha-HSD3|Chlordecone reductase homolog HAKRD|Dihydrodiol dehydrogenase 2 (DD-2, DD2)|Dihydrodiol dehydrogenase/bile acid-binding protein (DD/BABP)|Type III 3-alpha-hydroxysteroid dehydrogenase|AKR1C2|DDH2
Calculated MW 37 kDa
Protein ID P52895
Reactivity Human, Mouse, Rat
Applications ELISA, IF, WB
Recommended dilution WB: 1:500-1:2000; IF: 1:50-1:200