AHR antibody
£210.00
AHR antibody (FNab00231)
Product
| Cat # FNab00231 | Size 100ug |
Price
£210.00
|
Qty
|
Description
Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00231 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | aryl hydrocarbon receptor |
| Alternate Names | Aryl hydrocarbon receptor (Ah receptor, AhR)|Class E basic helix-loop-helix protein 76 (bHLHe76)|AHR|BHLHE76 |
| Calculated MW | 105 kDa |
| Protein ID | P35869 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, IP, WB |
| Recommended dilution | WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200 |
| Gene ID | 196 |