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ACAN antibody

£210.00

ACAN antibody (FNab00213)

Product

Cat #  FNab00213 Size  100ug Price 
£210.00
Qty 

Description

Aggrecan(ACAN), also named as CSPCP, AGC1 and MSK16, belongs to the aggrecan/versican proteoglycan family(also including versican, brevican and neurocan). It is a major component of extracellular matrix of cartilagenous tissues. A major function of aggrecan is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. This polyclonal antibody raised against 1-298aa of human aggrecan reveals a band of 70 kDa, which is consistent with the molecular weight of degradation product generated by proteolysis at the aggrecanase site(PMID: 7852317; 9337874).

Specifications

Manufacturer FineTest
Manufacturer Cat# FNab00213
Product Size 100ug
Antibody Type Polyclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Immunogen affinity purified
Purity ≥95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Immunogen aggrecan
Alternate Names Aggrecan core protein|Cartilage-specific proteoglycan core protein (CSPCP)|Chondroitin sulfate proteoglycan core protein 1 (Chondroitin sulfate proteoglycan 1)|Aggrecan core protein 2|ACAN|AGC1|CSPG1|MSK16
Calculated MW 70 kDa, 250-260 kDa
Protein ID P16112
Reactivity Human, Mouse, Rat
Applications ELISA, IHC, WB
Recommended dilution WB: 1:500-1:1000; IHC: 1:20-1:200