anti- ACVRL1 antibody

anti- ACVRL1 antibody

Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Cat# Size Price Qty Buy
FNab00131 100µg £210.00

Additional Information

Property Value or Rating
Product Size 100µg
Manufacturer FineTest
Antibody Type polyclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Immunogen affinity purified
Purity ≥95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Immunogen activin A receptor type II-like 1
Alternate Names Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I
Calculated MW 56 kDa
Protein ID P37023
Reactivity Human
Applications ELISA, FC, IHC, IP, WB
Recommended dilution WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000
Gene ID 94

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