ACTN4 antibody
£210.00
ACTN4 antibody (FNab00123)
Product
| Cat # FNab00123 | Size 100ug |
Price
£210.00
|
Qty
|
Description
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00123 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | actinin, alpha 4 |
| Alternate Names | Alpha-actinin-4|Non-muscle alpha-actinin 4|ACTN4 |
| Calculated MW | 105 kDa |
| Protein ID | O43707 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, FC, IF, IHC, IP, WB |
| Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000; IF: 1:10-1:100 |
| Gene ID | 81 |