anti- ACTN4 antibody

anti- ACTN4 antibody

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein(Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation(PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions(By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA(PubMed:22351778).
Cat# Size Price Qty Buy
FNab00123 100µg £210.00

Additional Information

Property Value or Rating
Product Size 100µg
Manufacturer FineTest
Antibody Type polyclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Immunogen affinity purified
Purity ≥95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Immunogen actinin, alpha 4
Alternate Names ACTININ 4, actinin, alpha 4, ACTN4, Alpha actinin 4, DKFZp686K23158, F actin cross linking protein, FSGS, FSGS1, Non muscle alpha actinin 4
Calculated MW 105 kDa
Protein ID O43707
Reactivity Human, Mouse, Rat
Applications ELISA, FC, IF, IHC, IP, WB
Recommended dilution WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000; IF: 1:10-1:100
Gene ID 81

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