ACOX1 antibody
£210.00
ACOX1 antibody (FNab00095)
Product
| Cat # FNab00095 | Size 100ug |
Price
£210.00
|
Qty
|
Description
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.It has 3 isoforms produced by alternative splicing with the molecular mass of 70-74 kDa and can be cleaved post-translationally into a 50-kDa and a 22-kDa subunit between Val468 and Ala469 (PMID: 10672038).
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00095 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | acyl-Coenzyme A oxidase 1, palmitoyl |
| Alternate Names | Peroxisomal acyl-coenzyme A oxidase 1 (AOX)|Palmitoyl-CoA oxidase|Peroxisomal fatty acyl-CoA oxidase|Straight-chain acyl-CoA oxidase (SCOX)|Peroxisomal acyl-CoA oxidase 1, A chain|Peroxisomal acyl-CoA oxidase 1, B chain|Peroxisomal acyl-CoA oxidase 1, C chain|ACOX1|ACOX |
| Calculated MW | 74 kDa |
| Protein ID | Q15067 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200 |
| Gene ID | 51 |