ACD antibody
£210.00
ACD antibody (FNab00078)
Product
| Cat # FNab00078 | Size 100ug |
Price
£210.00
|
Qty
|
Description
Component of the shelterin complex(telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00078 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | adrenocortical dysplasia homolog(Mouse) |
| Alternate Names | Adrenocortical dysplasia protein homolog|POT1 and TIN2-interacting protein|ACD|PIP1|PTOP|TINT1|TPP1 |
| Calculated MW | 58 kDa |
| Protein ID | Q96AP0 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Recommended dilution | WB: 1:500-1:5000 |
| Gene ID | 65057 |