ABHD2 antibody
£227.50
ABHD2 antibody (FNab00049)
Product
| Cat # FNab00049 | Size 100ug |
Price
£227.50
|
Qty
|
Description
Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol(AG) from cell membrane(PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol(1AG) and 2-arachidonoylglycerol(2AG) to glycerol and arachidonic acid(AA)(PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation(PubMed:26989199). May also play a role in smooth muscle cells migration(By similarity).
Specifications
| Manufacturer | FineTest |
|---|---|
| Manufacturer Cat# | FNab00049 |
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | abhydrolase domain containing 2 |
| Alternate Names | Monoacylglycerol lipase ABHD2|2-arachidonoylglycerol hydrolase|Abhydrolase domain-containing protein 2|Acetylesterase|Lung alpha/beta hydrolase 2|Progesterone-sensitive lipase|Protein PHPS1-2|ABHD2|LABH2 |
| Calculated MW | 48 kDa |
| Protein ID | P08910 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Recommended dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 |
| Gene ID | 11057 |