Angiotensin-Converting Enzyme 2 (NT) Blocking Peptide
£103.13
Angiotensin-Converting Enzyme 2 (NT) Blocking Peptide (A297-50ug)
Product
| Cat # A297-50ug | Size 50 µg |
Price
£103.13
|
Qty
|
Description
Angiotensin I converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9].1 ,or the conversion of angiotensin II to angiotensin 1-7.2 ACE 2 has direct effects on cardiac function2, and is expressed predominantly in vascular endothelial cells of the heart and the kidneys.3 ACE2 plays a regulatory role in lung pathophysiology, including pulmonary fibrosis and acute lung disease. Activation of ACE2 by a small molecule can be a therapeutically relevant approach for treating and controlling Pulmonary Hypertension (PH).4 ACE2 may also have clinical potential as a novel molecular target for the treatment of pancreatic ductal adenocarcinoma (PDAC).5
Specifications
| Manufacturer Cat# | A297 |
|---|---|
| Product Size | 50 µg |
| Concentration | 0.2 mg/ml |
| Formulation | This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. |
| Alternate Names | Blocking Peptide Angiotensin-Converting Enzyme 2 ACEH ACE2 Human ACEH Angiotensin-Converting Enzyme 2 (NT) Blocking Peptide |
| Target | Angiotensin-Converting Enzyme 2 |
| Storage | Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | Angiotensin-Converting Enzyme 2 |