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AMG 487

Selleck

AMG 487 (S8682-GRP)

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Description

AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8.0 nM and 8.2 nM, respectively.

Specifications

Manufacturer Cat# S8682
Target CXCR