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AMG-47a

Selleck

AMG-47a (S2213-GRP)

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Description

AMG-47a is a potent, nonselective inhibitor of Lck kinase with IC50 of 3.4 uM and it also inhibits T cell proliferation. AMG-47a exhibit anti-inflammatory activity (ED50) of 11 mg/kg in the anti-CD3-induced production of interleukin-2 (IL-2) in mice.

Specifications

Manufacturer Cat# S2213
Target Src