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AM-9747

AM-9747 (E1481-GRP)

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Description

AM-9747 (PRMT5-IN-25) is a potent inhibitor of PRMT5 with a Ki of 0.06 nM. It exhibits antiproliferative activity and a significant oral antitumor effect in mouse models employing patient-derived xenografts (PDX).

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E1481
Target PRMT