Alisertib (MLN8237)
Products
Description
Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Alisertib induces cell cycle arrest, apoptosis and autophagy. Phase 3.
Specifications
| Manufacturer Cat# | S1133 |
|---|---|
| Target | Aurora Kinase |