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AG-490

Selleck

AG-490 (S1143-GRP)

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Description

AG-490 is an inhibitor of EGFR with IC50 of 0.1 μM in cell-free assays, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.

Specifications

Manufacturer Cat# S1143
Target EGFR