AffiPure™ Normal Bovine IgG, Whole Molecule (B662-10mg)

Normal Bovine IgG Ultra, Whole Molecule was purified using protein G chromatography fromnormal serum. IgG is produced and secreted by plasma B cells, and constitutes the majority of serumimmunoglobulins. The whole IgG molecule contains both the F(c) region, recognized by high-affinity Fcreceptor proteins, and the F(ab) region with the epitope-recognition site, and thus contains two antigenbinding sites. IgG antibodies mediate immunological responses to allergy and pathogenic infections bybinding to viruses, bacteria, or fungi and facilitating their destruction by activation of the complimentcascade, immobilizing them via agglutination, or opsinization for phagocytosis. This product contains asufficient quantity of endogenous IgG to block nonspecific binding sites on fixed samples and assaysubstrates. While most commonly used in flow cytometry this product is useful in other applicationssuch as ELISA, IHC, ICC, Blocking and as a control.