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AD1058

AD1058 (E6572-GRP)

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Description

AD1058 is an orally bioavailable ATR inhibitor with blood-brain barrier permeability (IC50 = 1.6 nM). It demonstrates antitumor effects through inhibition of tumor cell proliferation, induction of cell cycle arrest, and promotion of apoptosis. This compound is applicable for studies involving advanced malignancies and brain metastases.

Specifications

Manufacturer Selleck Chemicals LLC
Manufacturer Cat# E6572