Actinomycin D cryst. research grade (10710.01)

Chromopeptide with antibiotic activity. Contains 2 cyclic peptides bound to the chromophoric phenoxazone ring. Binds specifically to the minor groove of the DNA double helix, and thus prevents it from being a template for RNA synthesis. Antineoplastic agent which inhibits the growth of rapidly dividing cells. Induces apoptosis in cancer cells. Used as a selective agent in cell culture.