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AC480 (BMS-599626)

Selleck

AC480 (BMS-599626) (S1056-GRP)

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Description

AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1.

Specifications

Manufacturer Cat# S1056
Target EGFR