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Ac-FLTD-CMK

Selleck

Ac-FLTD-CMK (S9817-GRP)

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Description

Ac-FLTD-CMK is a specific inhibitor for inflammatory caspases. Ac-FLTD-CMK inhibits gasdermin D (GSDMD) cleavage by caspases-1, -4, -5, and -11 in vitro. Ac-FLTD-CMK is effective against caspases-1, caspases-4 and caspases-5 with IC50 of 46.7 nM, 1.49 μM and 329 nM, respectively.

Specifications

Manufacturer Cat# S9817
Target Pyroptosis