8-OHDG antibody
£262.50
8-OHDG antibody (FNab11005)
Product
| Cat # FNab11005 | Size 100ug |
Price
£262.50
|
Qty
|
Description
8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.
Specifications
| Manufacturer Cat# | FNab11005 |
|---|---|
| Product Size | 100ug |
| Antibody Type | Polyclonal |
| Storage | PBS with 0.06% PC300 and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Physical Appearance | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | KLH conjugated 8-OHdG |
| Alternate Names | 8-hydroxy-2'-deoxyguanosine|2'-Deoxy-8-oxoguanosine|7,8-Dihydro-8-oxo-2'-deoxyguanosine|8-Oxo-7,8-dihydro-2'-deoxyguanosine|8-Oxo-7,8-dihydrodeoxyguanosine|2'-Deoxy-8-oxo-D-guanosine|8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG|2'-Deoxy-8-hydroxyguanosine |
| Reactivity | Species independent |
| Applications | IF, IHC |
| Recommended dilution | IHC: 1:50 - 1:500; IF: 1:50 - 1:200 |