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(3R,4S)-Tofacitinib

Selleck

(3R,4S)-Tofacitinib (E6023-GRP)

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Description

(3R,4S)-Tofacitinib is a less active enantiomer of Tofacitinib and a first-in-class inhibitor of JAK3 with an IC50 of 1 nM. It is highly efficacious in treating rheumatoid arthritis (RA).

Specifications

Manufacturer Cat# E6023
Target JAK