Tetradecenoic acid (cis-9)Tetradecenoic acid (cis-9)
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Tetradecenoic acid (cis-9)

Myristoleic acid; C14:1 (cis-9) Fatty acid

This high purity myristoleic acid is ideal as a standard and for biological studies. Myristoleic acid is a natural but uncommon fatty acid produced from myristic acid by the delta-9-desatuase enzyme. When esterified with cetyl alcohol myristoleic acid becomes cetyl mytistoleate, a compound with multiple biological properties including anti-infammitory, pain relief and immune system modulation. Extracts from Serenoa repens have been used to cause cell death in prostate cancer cells and myristoleic acid has been identified as at least one of the cytotoxic components of the extract.1 Myristoleic acid has been shown to suppress growth of hamster flank organs by inhibiting the 5alpha-reductase enzyme and thereby preventing the conversion of testosterone to 5alpha-dihydrotestosterone.2 Among the bioactive products in bovine whey that help to promote health and prevent disease is myristoleic acid which inhbits the germination of the pathogenic Candida albicans.3 Myristoleic acid has shown some anticarcinogenic effects by inhibiting the nuclear density of chemically induced transformation cells.4 A seaweed Ascophyllum nodosum extract has been shown to cause an increase of myristoleic acid accumulation in adipose tissues.
Cat# Size Price Qty Buy
1157 100 mg £121.88

Additional Information

Property Value or Rating
Product Size 100 mg
Manufacturer Matreya, LLC
Empirical Formula C14H26O2
CAS# 544-64-9
Formula Weight 226
Solvent none
Source natural
Purity 99%
Analytical Methods GC, TLC
Natural Source plant
Solubility chloroform, hexane, ethyl ether
Physical Appearance liquid
Storage -20°C
Dry Ice No
Hazardous No
References

1. K. Hirano et al. “Myristoleic acid, a cytotoxic component in the extract from Serenoa repens, induces apoptosis and necrosis in human prostatic LNCaP cells” Prostate, vol. 47 pp. 59-64, 2001 
2. R. Hiipakka et al. “Growth suppression of hamster flank organs by topical application of catechins, alizarin, curcumin, and myristoleic acid” Archives of Dermatological Research, vol. 293 pp. 200-205, 2001 
3. P. Belhumeur et. al. “Whey-derived free fattyacids suppress the germination of Candida albicans invitro” FEMS Yeast Res, vol. 7 pp. 276-285, 2007 
4. S. Sharma, P. Gao, and V. Steele “Quantitative Morphometry of Respiratory Tract Epithelial Cells as a Tool for Testing Chemopreventive Agent Efficacy” Anticancer Research, vol. 3 pp. 737-742, 2010

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