Sulfatides, (bovine) (Na+ salt)Sulfatides, (bovine) (Na+ salt)
Move your mouse over image or click to enlarge

Sulfatides, (bovine) (Na+ salt)

Ceramide-galactoside-3-sulfate; Cerebroside sulfate

Sulfatide is a type of sulfolipid that is found primarily in the central nervous system and is a myelin-specific sphingolipid. A deficiency of sulfatide in white and gray matter has been associated with Alzheimer’s disease and other types of dementia. Apoliprotein E plays an important regulating role in the metabolism of sulfatides.1 A production of anti-sulfatide antibodies in the cerebrospinal fluid, leading to a deficiency in sulfatides, may be a cause of degeneration of the myelin sheath, leading to multiple sclerosis.2 Metachromatic leukodystrophy is an inherited disorder characterized by a deficiency of the lysosomal enzyme arylsulfatase A and the subsequent accumulation of sulfatide in neural and visceral tissues.3 An immunomodulatory role for sulfatides has been suggested in the pathogenesis of tuberculosis.
Cat# Size Price Qty Buy
1049 50 mg £487.50

Additional Information

Property Value or Rating
Product Size 50 mg
Manufacturer Matreya, LLC
Empirical Formula C42H80NNaO11S
CAS# 85496-63-5
Formula Weight 830 (stearoyl) Na+ Salt
Solvent none
Source natural
Purity 98+%
Analytical Methods TLC; identity confirmed by MS
Natural Source bovine
Solubility DMSO, chloroform/methanol/water, 2:1:0.1 (if needed, a few drops of acetic acid)
Physical Appearance solid
Storage -20°C
Dry Ice No
Hazardous No
References

1. Cheng H, Zhou Y, Holtzman DM, Han X., Neurobiology of Aging (2008) August
2. Ramesh C. Halder, A. Jahng, I. Maricic and Vipin Kumar, Neurochemical Research (2007) February, Vol. 32(2): 257 
3. Phillip D. Whitfield, Peter C. Sharp, David W. Johnson, Paul Nelson and Peter J. Meikle, Molecular Genetics and Metabolism (2001) May, Vol. 73(1):30

Related Documents