Nanoprobes, Inc

NanoprobesNanogold Labelling Reagents, Conjugates, Nanomaterials & Contrast Agents

Nanoprobes was founded in 1990 as a nanoparticle research company manufacturing some of the most sensitive reagents and technology for detecting biological molecules.

Nanoprobes has developed unique gold labeling technology using chemically cross-linked metal clusters and nanoparticles as labels. Unlike conventional immunogold probes, in which colloidal gold particles are electrostatically adsorbed to antibodies and proteins, their gold labels are uncharged molecules which are cross-linked to specific sites on biomolecules. This gives their probes a range and versatility which is not available with colloidal gold. Their labels can be attached to any molecule with a reactive group -- proteins, peptides, oligonucleotides, small molecules and lipids -- for detection and localization.

Nanoprobes has developed new technology to expand the uses of gold labels for sensitive and rapid medical diagnostics. AuroVist™ their new X-ray contrast agent gives the highest contrast of any blood contrast agent. They also offer a range of ancillary reagents for chemical amplification, staining and imaging.

 

Nanogold® Labelling ReagentsNanogold Labelling Reagents

Get incredible penetration and precision with a choice of reactive groups for 1.4nm Nanogold® or 0.8nm Undecagold. The 1.4 nm Nanogold® particle is a gold compound: it is not just adsorbed to proteins, like colloidal gold, but covalently reacts at specific sites under mild buffer conditions. Available with Gold and Silver labelling enhancers for EM, LM and Blots.

 

anti-tubulin primary antibody,(L) goat anti-mouse colloidal gold or (R) goat Fab' anti-mouse-NanogoldNanogold® Conjugates

A range of 1.4nm Nanogold® Conjugates are available -

Antibody Nanogold® Conjugates to a range of species withFab', IgG or Streptavidin

FluoroNanogold™ Conjugates give 2in 1 labeling for fluorescence and EM

Lipid Nanogold® Conjugates for study of membranes

 

AuroVist™ 15nm & 1.9nm X-ray Contrast AgentMicroCT of mouse inferior vena cava

Unparalleled for microCT - Highest contrast, longest half-life. Gold achieves better contrast than iodine for both micro-CT and clinical CT applications.

 

Gold Nanomaterials

5 nm and 3 nm functionalized gold nanoparticles are available with a range of solubility properties: hydrophilic, hydrophobic, and amphiphilic.

Showing 1-50 of 103 Products
  1. 1.8 nm Ni-NTA-Nanogold® (2080-3ml)

    £408.00
    Product Size: 3ml at 10uM
    1.8 nm gold particles functionalized with nickel (II) nitraloacetic acid (NTA) chelates. Use for localizing and detecting polyhistidine-tagged targets in protein complexes, cells or tissues. Smaller than antibody probes.
  2. 10 nm Ni-NTA-Nanogold® (2084)

    Starting at: £129.00

    Ni-NTA-Nanogold® for His-tagged recombinant protein localization and detection, electron and light microscopy and Western blots
  3. 3 nm Octanethiol stabilized gold nanoparticles (3015-80mg)

    £393.00
    Product Size: 80mg
    The thiol is covalently attached to 3 nm gold nanoparticles. Use in organic solvents such as toluene.
  4. 5 nm (1-mercaptoundec-11-yl) tetraethyleneglycol stabilized gold nanoparticles (3013-80mg)

    £372.00
    Product Size: 80mg
    The thiol is covalently attached to 5 nm gold nanoparticles. Soluble in alcohol and water.
  5. 5 nm 1-Mercapto-(triethylene glycol)methyl ether stabilized gold nanoparticles (3012-80mg)

    £372.00
    Product Size: 80mg
    The thiol is covalently attached to 5 nm gold nanoparticles. Soluble in a variety of solvents including toluene, chloroform, ethyl acetate, acetone, water and alcohols.
  6. 5 nm Dodecanethiol stabilized gold nanoparticles (3014-80mg)

    £324.00
    Product Size: 80mg
    The thiol is covalently attached to 5 nm gold nanoparticles. Use in organic solvents such as toluene.
  7. 5 nm Ni-NTA-Nanogold® (2082-3ml)

    £433.00
    Product Size: 3ml at 0.5uM
    5 nm gold particles functionalized with nickel (II) nitraloacetic acid (NTA) chelates. Use for localizing and detecting polyhistidine-tagged targets in protein complexes, cells or tissues. Go directly to EM without silver or gold enhancement!
  8. Alexa Fluor® 488 - FluoroNanogold™ Fab' goat anti guinea pig IgG (H+L) (7255)

    Starting at: £318.00

    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  9. Alexa Fluor® 488 - FluoroNanogold™ Fab' goat anti rabbit IgG (H+L) (min X Hu Sr Prot) (7204)

    Starting at: £318.00

    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  10. Alexa Fluor® 488 - FluoroNanogold™ Fab' goat anti rat IgG (H+L) (min X Hu, Bov, Hrs Sr Prot) (7208-0.5)

    £337.00
    Product Size: 0.5 ml
    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  11. Alexa Fluor® 488 - FluoroNanogold™ Fab' rabbit anti goat IgG (H+L) (min X Hu Sr Prot) (7206)

    Starting at: £371.00

    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  12. Alexa Fluor® 488 - FluoroNanogold™ Fab' rabbit anti sheep IgG (H+L) (7251)

    Starting at: £318.00

    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  13. Alexa Fluor® 488 - FluoroNanogold™ IgG goat anti guinea pig IgG (H+L) (7254)

    Starting at: £292.00

    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  14. Alexa Fluor® 488 - FluoroNanogold™ IgG goat anti rat IgG (H+L) (min X Hu, Bov, Hrs Sr Prot) (7207-0.5)

    £322.00
    Product Size: 0.5 ml
    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  15. Alexa Fluor® 488 - FluoroNanogold™ IgG rabbit anti goat IgG (H+L) (min X Hu Sr Prot) (7205)

    Starting at: £292.00

    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  16. Alexa Fluor® 488 - FluoroNanogold™ IgG rabbit anti sheep IgG (H+L) (7250)

    Starting at: £292.00

    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  17. Alexa Fluor® 488 - FluoroNanogold™ streptavidin (7216-0.5)

    £368.00
    Product Size: 0.5 ml
    Alexa Fluor® 488 FluoroNanogold™ Conjugates
  18. Alexa Fluor® 546 - FluoroNanogold™ Fab' goat anti guinea pig IgG (H+L) (7455)

    Starting at: £318.00

    Alexa Fluor® 546 FluoroNanogold™ Conjugates
  19. Alexa Fluor® 546 - FluoroNanogold™ Fab' goat anti rabbit IgG (H+L) (min X Hu Sr Prot) (7404)

    Starting at: £318.00

    Alexa Fluor® 546 FluoroNanogold™ Conjugates
  20. Alexa Fluor® 546 - FluoroNanogold™ streptavidin (7416-0.5)

    £368.00
    Product Size: 0.5 ml
    Alexa Fluor® 546 FluoroNanogold™ Conjugates
  21. Alexa Fluor® 546 - FluoroNanogold™IgG goat anti guinea pig IgG (H+L) (7454)

    Starting at: £292.00

    Alexa Fluor® 546 FluoroNanogold™ Conjugates
  22. Alexa Fluor® 594 - FluoroNanogold™ Fab' goat anti guinea pig IgG (H+L) (7355)

    Starting at: £318.00

    Alexa Fluor® 594 FluoroNanogold™ Conjugates
  23. Alexa Fluor® 594 - FluoroNanogold™ Fab' goat anti rabbit IgG (H+L) (min X Hu Sr Prot) (7304)

    Starting at: £318.00

    Alexa Fluor® 594 FluoroNanogold™ Conjugates
  24. Alexa Fluor® 594 - FluoroNanogold™ IgG goat anti guinea pig IgG (H+L) (7354)

    Starting at: £292.00

    Alexa Fluor® 594 FluoroNanogold™ Conjugates
  25. Alexa Fluor® 594 - FluoroNanogold™ streptavidin (7316-0.5)

    £368.00
    Product Size: 0.5 ml
    Alexa Fluor® 594 FluoroNanogold™ Conjugates
  26. Alexa Fluor® 647 - FluoroNanogold™ Fab' goat anti rabbit IgG (H+L) (min X Hu Sr Prot) (7504)

    Starting at: £318.00

    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  27. Alexa Fluor® 647 - FluoroNanogold™ Fab' goat anti rat IgG (H+L) (min X Hu, Bov, Hrs Sr Prot) (7508-0.5)

    £337.00
    Product Size: 0.5 ml
    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  28. Alexa Fluor® 647 - FluoroNanogold™ Fab' rabbit anti goat IgG (H+L) (min X Hu Sr Prot) (7506-0.5)

    £371.00
    Product Size: 0.5 ml
    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  29. Alexa Fluor® 647 - FluoroNanogold™ goat anti Guinea Pig IgG (H+L) (7554-0.5)

    £292.00
    Product Size: 0.5 ml
    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  30. Alexa Fluor® 647 - FluoroNanogold™ streptavidin (7516-0.5)

    £368.00
    Product Size: 0.5 ml
    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  31. Alexa Fluor® 647 - FluoroNanogold™IgG goat anti human IgG (H+L) (min X Bov, Hrs, Ms Sr Prot) (7552)

    Starting at: £292.00

    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  32. Alexa Fluor® 647 - FluoroNanogold™IgG goat anti rat IgG (H+L) (min X Hu, Bov, Hrs Sr Prot) (7507-0.5)

    £322.00
    Product Size: 0.5 ml
    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  33. Alexa Fluor® 647 - FluoroNanogold™IgG rabbit anti goat IgG (H+L) (min X Hu Sr Prot) (7505)

    Starting at: £292.00

    Alexa Fluor® 647 FluoroNanogold™ Conjugates
  34. Aurovist™ - 1.9 nm (1102)

    Starting at: £366.00

    1.9 nm gold nanoparticles containing 40 mg gold metal. Ready to be reconstituted in water, PBS, or other buffer.
  35. Aurovist™ - 15 nm (1115)

    Starting at: £270.00

    15 nm gold nanoparticles containing 40 mg gold metal. Supplied dissolved in 0.2 mL phosphate buffered saline (PBS: 20 mM sodium phosphate with 150 mM sodium chloride, pH 7.4), filtered through a 0.22 µm filter.