Recombinant Human ApoE3Recombinant Human ApoE3
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Recombinant Human ApoE3

Apolipoprotein E (ApoE) is a 299 amino acid protein, produced by the liver and circulating macrophages, that is a constituent of every plasma lipoprotein except the smallest low density lipoproteins (LDL). It is a key player in the recycling and redistribution of lipids and cholesterol. ApoE is a ligand with a high affinity for low density lipoprotein receptors (LDLR). It regulates the activity of enzymes that metabolize lipids and also makes lipids soluble. Mice and humans that lack ApoE cannot remove excess lipoproteins from the plasma and have an increased risk of atherosclerosis. Defective binding of ApoE to its receptors will lead to accumulation of cholesterol-rich lipoprotein particles in the plasma; this is the cause of type III hyperlipoproteinemia. There are three main isoforms of ApoE all products of alleles at a single gene locus: E2 (Cys112, Cys158), E3 (C112, Arg158), and E4 (Arg112, Arg158). ApoE3 is the most common isoform and is present in 40-90% of the population.
Cat# Size Price Qty Buy
A218-500ug 500 μg £328.13

Additional Information

Property Value or Rating
Manufacturer Cat# A218
Product Size 500 μg
Manufacturer Leinco Technologies Inc
Alternate Names Recombinant Protein Apolipoprotein E3 Apoprotein E3 ApoE3 Human ApoE3 Recombinant Human ApoE3
Storage -20°C to -70°C
Protein Apolipoprotein E3

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