rac-beta-Tocopherol/ml 1ml hexanerac-beta-Tocopherol/ml 1ml hexane
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rac-beta-Tocopherol/ml 1ml hexane

5,8-Dimethyltocol

beta-tocopherol is one of the forms of vitamin E, which is well known for its antioxidant activity.1,2 beta-tocopherol, due to its having only one methyl group ortho to the phenolic hydroxyl group, has slightly less antioxidant activity in vivo than alpha-tocopherol which has two ortho-methyl groups. Vitamin E inhibits lipid oxidation by donating its phenolic hydrogen to lipid free radicals.3 Antioxidant activity in vivo is normally lpha>beta>delta>gamma but the antioxidant potency may depend on various chemical and physical situations.4 The ortho-methyl substitution of the chroman head plays a vital role in the antioxidant activity of tocopherols while the phytyl tail is very important for proper positioning in the biomembranes. The antioxidant properties of vitamin E may delay memory loss in Down’s syndrome patients due to their protection from harmful oxidation caused by excess activity of Superoxide dismutase. Vitamin E is only naturally produced in plants, algae, and some cyanobacteria and is therefore an important dietary nutrient for humans and animals.
Cat# Size Price Qty Buy
1071 50 mg/ml, 1ml £226.88

Additional Information

Property Value or Rating
Product Size 50 mg/ml, 1ml
Manufacturer Matreya, LLC
Empirical Formula C28H48O2
CAS# 148-03-8
Formula Weight 417
Solvent hexane
Source synthetic
Purity TLC 95%, GC 98%, HPLC 98%
Analytical Methods TLC, GC, HPLC; identity confirmed by MS
Solubility methanol, ethanol, hexane, chloroform
Physical Appearance liquid
Storage -20°C
Dry Ice No
Hazardous Yes
References

1. Afaf Kamal-Eldin and Lars-Ake Appelqvist The chemistry and antioxidant properties of tocopherols and tocotrienols, Lipids, July; 31 (7): 671-701, 1996 
2. G. W. Burton, and M. G. Traber Vitamin E: Antioxidant Activity, Biokinetics, and Bioavailability, Annual Review of Nutrition, July Vol. 10: 357-382, 1990 
3. G. W. Burton and K. Ingold Autoxidation of biological molecules. 1. Antioxidant activity of vitamin E and related chain-breaking phenolic antioxidants in vitro, U. J. Am. Chem. Soc., 103, 6472-6477, 1981 
4. Anchalee Sirikhachornkit, Jai W. Shin, Irene Baroli, and Krishna K. Niyogi Replacement of a -tocopherol by ß -tocopherol enhances resistance to photo-oxidative stress in a xanthophyll-deficient strain of Chlamydomonas reinhardtii, Eukaryotic Cell, doi:10.1128, 2009

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