Product Uses Include
- Promote tubulin polymerization in vitro
- Promote microtubule stability in vitro
- Anti-mitotic drug in cell cultures
Material
Paclitaxel's (Taxol) usefulness as a laboratory tool is well established and lies in its ability to inhibit microtubule depolymerization. Thus, taxol stabilized microtubules are used as substrates for the identification and characterization of the ever increasing number of microtubule associated proteins.
Paclitaxel is provided as a lyophilized powder. DMSO for resuspension is supplied with the product. When resuspended the paclitaxel is at 2 mM concentration.
Purity
In keeping with our policy of providing only the highest quality products, we are now pleased to inform you that Cytoskeleton is offering paclitaxel (taxol), from the Pacific yew tree, Taxus brevifolia, at a chromatographic purity of >99.5%. This is the purest taxol commercially available for research use.
Biological Activity
We have determined that the microtubule stabilizing property of our product is equal or superior to any other commercially available taxols. Microtubules in 10 µM paclitaxel are stable at room temperature for over one week.
