Octadecadienoic acid (all cis-9,12)Octadecadienoic acid (all cis-9,12)
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Octadecadienoic acid (all cis-9,12)

C18:2 (all cis-9,12) Fatty acid; Linoleic acid

Linoleic acid is an 18 carbon, omega-6 fatty acid that is abundant in many plant oils. It is an essential fatty acid in animals and is the precursor in the synthesis of arachidonic acid and other polyunsaturated fatty acids. The conjugated linoleic acids c9,t11 and t10,c12 inhibit linoleic acid elongation to eicosadienoic acid.1 Linoleic acid supplements have been used to try to help prevent cystic fibrosis, dermatitis, and diabetes but the precise mechanisms have proven elusive. It is commonly used in dermatological cosmetics, soaps, and emulsifiers. In some fungus linoleic acid is converted to oxylipins, important compounds of the fungal life cycle,2 and it may play a direct role in the epidermal permeability barrier.3
Cat# Size Price Qty Buy
1024 1 gram £70.31

Additional Information

Property Value or Rating
Product Size 1 gram
Manufacturer Matreya, LLC
Empirical Formula C18H32O2
CAS# 60-33-3
Formula Weight 280
Solvent none
Source natural
Purity 99%
Analytical Methods GC, TLC
Natural Source plant
Solubility hexane, ethyl ether, ethanol
Physical Appearance liquid
Storage -20°C
Dry Ice No
Hazardous No
References

1. L. Chuang et al. “Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase” Lipids, Vol. 36(10), pp. 1099-1103, 2001 
2. M. Wadman et al. “Conversion of linoleic acid into novel oxylipins by the mushroom Agaricus bisporus” Lipids, Vol. 40(11) pp. 1163-1170, 2005 
3. P. Elias, B. Brown, V. Ziboh “The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in Barrier Function” Journal of Investigative Dermatology, Vol.74 pp. 230–233, 1980

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