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Neutral Protease NB GMP Grade

Alone or in Combination with other GMP Collagenases

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Neutral Protease is a metalloprotease that can cleave peptide bonds in proteins such as collagen, proteoglycan, fibronectin, elastin etc. Due to these properties, it is suitable for the isolation of a broad range of cell types by tissue dissociation. In combination with Collagenase NB 1 GMP Grade, Neutral Protease NB GMP Grade is especially suited for isolation of islets of Langerhans from human pancreas. However, Neutral Protease NB GMP Grade can also be used in combination with Collagenase NB 6 GMP Grade for applications like tissue engineering and transplantation into humans which have to meet GMP requirements .

Cat#	Size	Price	Qty	Buy
N0002936	≥ 100 U (DMC)	£933.50

Additional Information

Property	Value or Rating
Product Size	≥ 100 U (DMC)
Manufacturer	Nordmark Biochemicals
Storage	+2 °C to +8 °C
References	References and Definitions Unit definition: Neutral Protease: 1 DMC Unit catalyzes the cleavage of 1 µmole peptide bond from dimethylcasein per minute at 25 °C, pH 7.0, expressed in terms of newly formed terminal amino groups, determined with TNBS (1). Endotoxin: Ph. Eur. (1 Endotoxin Unit is equal to 1 International Unit of a WHO approved reference standard endotoxin (RSE)). References: 1. Lin, Y.-C. et al. (1969) J. Biol. Chem. 244, 789-93.

References and Definitions

Unit definition:
Neutral Protease: 1 DMC Unit catalyzes the cleavage of 1 µmole peptide bond from dimethylcasein per minute at 25 °C, pH 7.0, expressed in terms of newly formed terminal amino groups, determined with TNBS (1).
Endotoxin: Ph. Eur. (1 Endotoxin Unit is equal to 1 International Unit of a WHO approved reference standard endotoxin (RSE)).

References:
1. Lin, Y.-C. et al. (1969) J. Biol. Chem. 244, 789-93.

Neutral Protease NB GMP Grade

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Neutral Protease NB GMP Grade

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